Helix Bio — the lab operating system

From hypothesis to signed result in one loop.

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kinase-panel-v3.helix

test 12 compounds against KRAS-G12C

dose 10 µM → 0.5 nM, half-log, 11 points

replicates 3 · controls DMSO, sotorasib

readout luminescence @ 24 h

✓ compiled · 384 wells · 2 plates

HX-0412 · 1/2Dispensing · row F
0.5 nM10 µM
IC₅₀42.7 nMSigned bundle · sha 9f3c…a10e
  1. 01Design
  2. 02Run
  3. 03Analyse
  4. 04Share

01Design

Write the protocol once. In plain language.

Describe the experiment the way you’d explain it to a colleague. Helix compiles it into a validated plate map with controls, replicates and randomised well positions.

38 minmedian time from idea to a runnable 384-well plan

02Run

Robots run it overnight. You sleep.

Plans dispatch to liquid handlers, incubators and readers across your bench. Every pipetting step is logged with volume, tip and timestamp — no more lab-notebook archaeology.

11,204plates executed last month across 62 partner labs

03Analyse

Results arrive already curve-fitted.

Dose–response fits, Z′ factors and outlier flags compute as the reader streams. Bad wells are caught at 3 a.m., not at Monday stand-up.

Z′ 0.81average assay quality on the platform this quarter

04Share

Every result is reproducible by default.

Publish the protocol, raw reads and analysis as one signed bundle. A collaborator in Basel can rerun your exact experiment on their own hardware.

94%of shared runs reproduced within ±5% on first attempt